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martedì 6 giugno 2017

# s-cell: turning stem cells into whatever you want (!)

<< an international team of researchers has a two-part system that can convert the cells to the targets and then remove the remnants of that conversion, leaving only the desired DNA behind to duplicate >>

AA << are using a Tet-On 3G inducible PiggyBac system that is a plasmid they named XLone to achieve insertion, activation and removal >>

A'ndrea Elyse Messer. Two-part system turns stem cells into whatever you want. June 5, 2017

http://news.psu.edu/story/470575/2017/06/05/research/two-part-system-turns-stem-cells-whatever-you-want

Lauren N. Randolph, Xiaoping Bao, et al. An all-in-one, Tet-On 3G inducible PiggyBac system for human pluripotent stem cells and derivatives. Scientific Reports 7, Article number: 1549 (2017) doi: 10.1038/s41598-017-01684-6

https://www.nature.com/articles/s41598-017-01684-6

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