<< This is the conclusion of Rigor Mortis, a wide-ranging critique of the modern biomedical research ecosystem by science journalist Richard Harris. He describes how a growing number of claims over the past decade that many published research findings are false, or at least not as robust as they should be, has led to calls for change, and the birth of a new discipline of metascience. >>
Marcus Munafo'. Metascience: Reproducibility blues. Nature 543, 619–620 (30 March 2017) doi:10.1038/543619a Pub 29 Mar2017
Richard F. Harris. Rigor Mortis: How Sloppy Science Creates Worthless Cures, Crushes Hope, and Wastes Billions. Basic: 2017.