<< We used a rodent analog of the Iowa Gambling Task to determine whether the addition of audiovisual cues would affect choice preferences. Adding reward-concurrent cues significantly increased risky choice. This is the first clear demonstration that reward-paired cues can bias cost/ benefit decision making against a subject's best interests in a manner concordant with elevated addiction susceptibility >>
Barrus MM, Winstanley CA. Dopamine D3 Receptors Modulate the Ability of Win-Paired Cues to Increase Risky Choice in a Rat Gambling Task. J Neurosci. 2016 Jan 20;36(3):785-94. doi: 10.1523/JNEUROSCI.2225-15.2016.